22. MICROBIOLOGICAL AND RADIOGRAPHIC FEATURES OF PATIENTS WITH INVASIVE PULMONARY ASPERGILLOSIS INFECTION IN NATIONAL LUNG HOSPITAL
Main Article Content
Abstract
Objective: To describe the microbiological and radiographic features of patients with invasive pulmonary Aspergillosis treated at the National Lung Hospital.
Methods: Retrospective descriptive study on 47 patients with invasive pulmonary Aspergillosis, treated at the National Lung Hospital from January 2019 to December 2020.
Results: The average age was 54 ± 14 years old. Patients had host factors of EORTC/MSG were 63.8%, mainly hematological malignancies (34%) and long-term corticosteroid use (23.4%). Bronchoscopy features: Pseudomembrane (35.5%), necrotic nodule (21.9%), ulcer (20.6%), warty lesion, infiltration, purulent exudates were range from 10-14%. The most common lung lesions on chest CT are nodules (70.2%), consolidations (51.1%), and cavities (27.7%), multiple lesions appearing in both sides. Microbiological findings: sputum culture (50%), bronchoalveolar lavage culture (45.5%); blood galactomannan (66.7%), bronchoalveolar lavage galactomannan (40%); blood Aspergillus-specific lateral-flow device (LFD Aspergillus) (71.4%), bronchoalveolar lavage LFD Aspergillus (66.7%).
Conclusion: Invasive pulmonary Aspergillosis has been reported increasingly. Early diagnosis and treatment reduce mortality. Combining the host factors, microbiological findings, and radiographic features helps clinicians establish diagnosis.
Article Details
Keywords
Aspergilloma, invasive aspergillosis, microbiology, lung lesion.
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